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A Powerful and Robust Method for Mapping Quantitative Trait Loci in General Pedigrees

The variance-components model is the method of choice for mapping quantitative trait loci in general human pedigrees. This model assumes normally distributed trait values and includes a major gene effect, random polygenic and environmental effects, and covariate effects. Violation of the normality a...

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Detalles Bibliográficos
Main Authors: Diao, G. , Lin, D. Y. 
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Human Genetics 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226198/
https://ncbi.nlm.nih.gov/pubmed/15918154
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