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A Powerful and Robust Method for Mapping Quantitative Trait Loci in General Pedigrees
The variance-components model is the method of choice for mapping quantitative trait loci in general human pedigrees. This model assumes normally distributed trait values and includes a major gene effect, random polygenic and environmental effects, and covariate effects. Violation of the normality a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Human Genetics
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1226198/ https://ncbi.nlm.nih.gov/pubmed/15918154 |
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