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Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping.

Homozygosity mapping is a powerful strategy for mapping rare recessive traits in children of consanguineous marriages. Practical applications of this strategy are currently limited by the inability of conventional linkage analysis software to compute, in reasonable time, multipoint LOD scores for pe...

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Detalhes bibliográficos
Main Authors: Kruglyak, L, Daly, M J, Lander, E S
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801139/
https://ncbi.nlm.nih.gov/pubmed/7847388
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