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Efficient Multipoint Linkage Analysis through Reduction of Inheritance Space

Computational constraints currently limit exact multipoint linkage analysis to pedigrees of moderate size. We introduce new algorithms that allow analysis of larger pedigrees by reducing the time and memory requirements of the computation. We use the observed pedigree genotypes to reduce the number...

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Bibliografske podrobnosti
Main Authors: Markianos, Kyriacos, Daly, Mark J., Kruglyak, Leonid
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275650/
https://ncbi.nlm.nih.gov/pubmed/11254453
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