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The sumLINK statistic for genetic linkage analysis in the presence of heterogeneity

We present the “sumLINK” statistic—the sum of multipoint LOD scores for the subset of pedigrees with nominally significant linkage evidence at a given locus—as an alternative to common methods to identify susceptibility loci in the presence of heterogeneity. We also suggest the “sumLOD” statistic (t...

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Bibliografski detalji
Glavni autori: Christensen, GB, Knight, S, Camp, NJ
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409837/
https://ncbi.nlm.nih.gov/pubmed/19217022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20414
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