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Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation
Topical application of nucleic acids offers many potential therapeutic advantages for suppressing genes in the skin, and potentially for systemic gene delivery. However, the epidermal barrier typically precludes entry of gene-suppressing therapy unless the barrier is disrupted. We now show that sphe...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409786/ https://ncbi.nlm.nih.gov/pubmed/22773805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118425109 |
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