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Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

Topical application of nucleic acids offers many potential therapeutic advantages for suppressing genes in the skin, and potentially for systemic gene delivery. However, the epidermal barrier typically precludes entry of gene-suppressing therapy unless the barrier is disrupted. We now show that sphe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zheng, Dan, Giljohann, David A., Chen, David L., Massich, Matthew D., Wang, Xiao-Qi, Iordanov, Hristo, Mirkin, Chad A., Paller, Amy S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409786/
https://ncbi.nlm.nih.gov/pubmed/22773805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118425109
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