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Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

Topical application of nucleic acids offers many potential therapeutic advantages for suppressing genes in the skin, and potentially for systemic gene delivery. However, the epidermal barrier typically precludes entry of gene-suppressing therapy unless the barrier is disrupted. We now show that sphe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zheng, Dan, Giljohann, David A., Chen, David L., Massich, Matthew D., Wang, Xiao-Qi, Iordanov, Hristo, Mirkin, Chad A., Paller, Amy S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409786/
https://ncbi.nlm.nih.gov/pubmed/22773805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118425109
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