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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
Microtubules are cytoskeleton filaments consisting of αβ-tubulin heterodimers. They switch between phases of growth and shrinkage. The underlying mechanism of this property, called dynamic instability, is not fully understood. Here, we identified a designed ankyrin repeat protein (DARPin) that inter...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409770/ https://ncbi.nlm.nih.gov/pubmed/22778434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204129109 |
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