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HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120
HIV-1 envelope glycoprotein is the primary target for HIV-1–specific antibodies. The native HIV-1 envelope spike on the virion surface is a trimer, but trimeric gp140 and monomeric gp120 currently are believed to induce comparable immune responses. Indeed, most studies on the immunogenicity of HIV-1...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409750/ https://ncbi.nlm.nih.gov/pubmed/22773820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204533109 |
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