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Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet
The natural four-letter genetic alphabet, comprised of just two base pairs (dA-dT and dG-dC), is conserved throughout all life, and its expansion by the development of a third, unnatural base pair has emerged as a central goal of chemical and synthetic biology. We recently developed a class of candi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409741/ https://ncbi.nlm.nih.gov/pubmed/22773812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205176109 |
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