JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate

The c-Jun NH(2)-terminal kinase (JNK) signal transduction pathway is implicated in cancer, but the role of JNK in tumorigenesis is poorly understood. Here, we demonstrate that the JNK signaling pathway reduces the development of invasive adenocarcinoma in the phosphatase and tensin homolog (Pten) co...

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Autori principali: Hübner, Anette, Mulholland, David J., Standen, Claire L., Karasarides, Maria, Cavanagh-Kyros, Julie, Barrett, Tamera, Chi, Hongbo, Greiner, Dale L., Tournier, Cathy, Sawyers, Charles L., Flavell, Richard A., Wu, Hong, Davis, Roger J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409732/
https://ncbi.nlm.nih.gov/pubmed/22753496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209660109
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