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Replicatively senescent cells are arrested in G1 and G2 phases

Most human somatic cells do not divide indefinitely but enter a terminal growth arrest termed replicative senescence. Replicatively senescent cells are generally believed to arrest in G1 or G0 stage of the cell cycle. While doing cell cycle analysis on three different lines of normal human fibroblas...

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Autori principali: Mao, Zhiyong, Ke, Zhonghe, Gorbunova, Vera, Seluanov, Andrei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409679/
https://ncbi.nlm.nih.gov/pubmed/22745179
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