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Impaired function of Fanconi anemia type C-deficient macrophages

FA is a genetic disorder characterized by BM failure, developmental defects, and cancer predisposition. Previous studies suggest that FA patients exhibit alterations in immunologic function. However, it is unclear whether the defects are immune cell-autonomous or secondary to leukopenia from evolvin...

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Autores principales: Liu, Ying, Ballman, Kimberly, Li, Deqiang, Khan, Shehnaz, Derr-Yellin, Ethel, Shou, Weinian, Haneline, Laura S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Leukocyte Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409636/
https://ncbi.nlm.nih.gov/pubmed/22106009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0811418
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