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Impaired function of Fanconi anemia type C-deficient macrophages

FA is a genetic disorder characterized by BM failure, developmental defects, and cancer predisposition. Previous studies suggest that FA patients exhibit alterations in immunologic function. However, it is unclear whether the defects are immune cell-autonomous or secondary to leukopenia from evolvin...

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Hlavní autoři: Liu, Ying, Ballman, Kimberly, Li, Deqiang, Khan, Shehnaz, Derr-Yellin, Ethel, Shou, Weinian, Haneline, Laura S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409636/
https://ncbi.nlm.nih.gov/pubmed/22106009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0811418
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