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Identification of PDE9 as a cGMP-specific phosphodiesterase in germinal vesicle oocytes: A proposed role in the resumption of meiosis

OBJECTIVE: To identify a cGMP-specific phosphodiesterase (PDE) in non-human primate germinal vesicle (GV) oocytes and establish a proposed effect on oocyte maturation through preliminary experiments in mouse GV oocytes. DESIGN: Controlled non-human primate and rodent experiments. SETTING: Academic r...

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Bibliografiske detaljer
Main Authors: Hanna, Carol B., Yao, Shan, Wu, Xuemei, Jensen, Jeffrey T.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409309/
https://ncbi.nlm.nih.gov/pubmed/22704629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2012.05.015
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