Axitinib Targeted Cancer Stemlike Cells to Enhance Efficacy of Chemotherapeutic Drugs via Inhibiting the Drug Transport Function of ABCG2

Stemlike cells have been isolated by their ability to efflux Hoechst 33342 dye and are called the side population (SP). We evaluated the effect of axitinib on targeting cancer stemlike cells and enhancing the efficacy of chemotherapeutical agents. We found that axitinib enhanced the cytotoxicity of...

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Autors principals: Wang, Fang, Mi, Yan-jun, Chen, Xing-Gui, Wu, Xing-ping, Liu, Zhenguo, Chen, Shu-peng, Liang, Yong-ju, Cheng, Chao, To, Kenneth Kin Wah, Fu, Li-wu
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409282/
https://ncbi.nlm.nih.gov/pubmed/22549112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00444
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