Mammalian DNA Is an Endogenous Danger Signal That Stimulates Local Synthesis and Release of Complement Factor B

Complement factor B plays a critical role in ischemic tissue injury and autoimmunity. Factor B is dynamically synthesized and released by cells outside of the liver, but the molecules that trigger local factor B synthesis and release during endogenous tissue injury have not been identified. We deter...

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Detalhes bibliográficos
Main Authors: Kaczorowski, David J, Scott, Melanie J, Pibris, John P, Afrazi, Amin, Nakao, Atsunori, Edmonds, Rebecca D, Kim, Sodam, Kwak, Joon H, Liu, Yujian, Fan, Jie, Billiar, Timothy R
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409274/
https://ncbi.nlm.nih.gov/pubmed/22526919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00011
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