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Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering
Understanding the quantitative functional consequences of human disease mutations requires silencing of endogenous genes and expression of mutants at close to physiological levels. Changing protein levels above or below these levels is also important for system perturbation and modelling. Fast desig...
में बचाया:
| में प्रकाशित: | Sci Rep |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661934/ https://ncbi.nlm.nih.gov/pubmed/26612112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17432 |
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