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Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering

Understanding the quantitative functional consequences of human disease mutations requires silencing of endogenous genes and expression of mutants at close to physiological levels. Changing protein levels above or below these levels is also important for system perturbation and modelling. Fast desig...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Beltran-Sastre, Violeta, Benisty, Hannah, Burnier, Julia, Berger, Imre, Serrano, Luis, Kiel, Christina
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661934/
https://ncbi.nlm.nih.gov/pubmed/26612112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17432
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