A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers

Cancer is principally considered a genetic disease, and numerous mutations are thought essential to drive its growth. However, the existence of genomically stable cancers and the emergence of mutations in genes that encode chromatin remodelers raise the possibility that perturbation of chromatin str...

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Detalhes bibliográficos
Main Authors: Lee, Ryan S., Stewart, Chip, Carter, Scott L., Ambrogio, Lauren, Cibulskis, Kristian, Sougnez, Carrie, Lawrence, Michael S., Auclair, Daniel, Mora, Jaume, Golub, Todd R., Biegel, Jaclyn A., Getz, Gad, Roberts, Charles W.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408754/
https://ncbi.nlm.nih.gov/pubmed/22797305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64400
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