Atypical teratoid/rhabdoid tumors—current concepts, advances in biology, and potential future therapies

Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in SMARCB1 (INI1, SNF5, BAF47) or, to a lesser extent, SMARCA4 (BRG1) of the SWItch/sucrose nonfermentable chromatin remodeling co...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Frühwald, Michael C., Biegel, Jaclyn A., Bourdeaut, Franck, Roberts, Charles W.M., Chi, Susan N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
Ämnen:
Invited Reviews
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864253/
https://ncbi.nlm.nih.gov/pubmed/26755072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov264
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