AGE-DEPENDENT REDUCTION OF THE PI3K REGULATORY SUBUNIT p85α SUPPRESSES PANCREATIC ACINAR CELL PROLIFERATION

The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is important for tissue proliferation. Previously, we found that tissue regeneration after partial pancreatic resection was markedly attenuated in aged mice as compared to young mice and that this attenuation was due to an age-dependent reduction...

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Hlavní autoři: Takahashi, Hitoshi, Okamura, Daiki, Starr, Marlene E., Saito, Hiroshi, Evers, B. Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408710/
https://ncbi.nlm.nih.gov/pubmed/22212451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00787.x
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