AGE-DEPENDENT REDUCTION OF THE PI3K REGULATORY SUBUNIT p85α SUPPRESSES PANCREATIC ACINAR CELL PROLIFERATION

The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is important for tissue proliferation. Previously, we found that tissue regeneration after partial pancreatic resection was markedly attenuated in aged mice as compared to young mice and that this attenuation was due to an age-dependent reduction...

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Main Authors: Takahashi, Hitoshi, Okamura, Daiki, Starr, Marlene E., Saito, Hiroshi, Evers, B. Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408710/
https://ncbi.nlm.nih.gov/pubmed/22212451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00787.x
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