Coagulation Factor IX for Hemophilia B Therapy


Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy. Reviewed herein are the current state in the manufacturing of FIX, improved variants of...

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Bibliografiska uppgifter
Huvudupphovsmän: Orlova, N. A., Kovnir, S. V., Vorobiev, I. I., Gabibov, A.G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: A.I. Gordeyev 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408704/
https://ncbi.nlm.nih.gov/pubmed/22872812
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