A Highly Productive CHO Cell Line Secreting Human Blood Clotting Factor IX

Hemophilia B patients suffer from an inherited blood-clotting defect and require regular administration of blood-clotting factor IX replacement therapy. Recombinant human factor IX produced in cultured CHO cells is nearly identical to natural, plasma-derived factor IX and is widely used in clinical...

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Publicado en:Acta Naturae
Autores principales: Kovnir, S. V., Orlova, N. A., Shakhparonov, M. I., Skryabin, K. G., Gabibov, A. G., Vorobiev, I. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: A.I. Gordeyev 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916734/
https://ncbi.nlm.nih.gov/pubmed/29713519
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