Coagulation Factor IX for Hemophilia B Therapy


Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy. Reviewed herein are the current state in the manufacturing of FIX, improved variants of...

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Bibliografske podrobnosti
Main Authors: Orlova, N. A., Kovnir, S. V., Vorobiev, I. I., Gabibov, A.G.
Format: Artigo
Jezik:Inglês
Izdano: A.I. Gordeyev 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408704/
https://ncbi.nlm.nih.gov/pubmed/22872812
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