Coagulation Factor IX for Hemophilia B Therapy


Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy. Reviewed herein are the current state in the manufacturing of FIX, improved variants of...

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Bibliographic Details
Main Authors: Orlova, N. A., Kovnir, S. V., Vorobiev, I. I., Gabibov, A.G.
Format: Artigo
Language:Inglês
Published: A.I. Gordeyev 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408704/
https://ncbi.nlm.nih.gov/pubmed/22872812
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