The Glucagon Receptor Is Involved in Mediating the Body Weight-Lowering Effects of Oxyntomodulin

Oxyntomodulin (OXM) is a peptide secreted postprandially from the L-cells of the gut that has a weak affinity for both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). Peripheral administration of OXM in humans and rodents causes weight loss reducing food intake and inc...

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Hlavní autoři: Kosinski, Jennifer R., Hubert, James, Carrington, Paul E., Chicchi, Gary G., Mu, James, Miller, Corey, Cao, Jin, Bianchi, Elisabetta, Pessi, Antonello, SinhaRoy, Ranabir, Marsh, Donald J., Pocai, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Integrative Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408645/
https://ncbi.nlm.nih.gov/pubmed/22421924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2012.67
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