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Cardiac Role of Cyclic-GMP Hydrolyzing Phosphodiesterase Type 5: From Experimental Models to Clinical Trials

Cyclic guanosine monophosphate (cGMP) and its primary signaling kinase, protein kinase G, play an important role in counterbalancing stress remodeling in the heart. Growing evidence supports a positive impact on a variety of cardiac disease conditions from the suppression of cGMP hydrolysis. The lat...

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Bibliografiske detaljer
Hovedforfatter: Kass, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408604/
https://ncbi.nlm.nih.gov/pubmed/22798047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11897-012-0101-0
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