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2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors

The affinity and efficacy at four subtypes (A(1), A(2A), A(2B) and A(3)) of human adenosine receptors (ARs) of a wide range of 2-substituted adenosine derivatives were evaluated using radioligand binding assays and a cyclic AMP functional assay in intact CHO cells stably expressing these receptors....

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Autori principali: Gao, Zhan-Guo, Mamedova, Liaman K., Chen, Peiran, Jacobson, Kenneth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408601/
https://ncbi.nlm.nih.gov/pubmed/15476669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2004.06.011
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