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alpha-DNA-III. Characterization by high field 1H-NMR, anti-parallel self-recognition and conformation of the unnatural hexadeoxyribonucleotides alpha-[d(CpApTpGpCpG)] and alpha-[d(CpGpCpApTpG)]. Alpha-oligodeoxynucleotides as potential cellular probes for gene control.

High field 2-D-1H-NMR techniques permitted the assignment of all non-exchangeable protons of the unnatural deoxyribonucleotides alpha-[d(CpApTpGpCpG)] and alpha-[d(CpGpCpApTpG)]. 1-D and 2-D NOESY experiments show strong H6H8-H4' dipolar interactions for all nucleotides in both sequences. These...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Morvan, F, Rayner, B, Imbach, J L, Chang, D K, Lown, J W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340845/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3588292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.10.4241
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