Synthesis, complete 1H assignments and conformations of the self-complementary hexadeoxyribonucleotide [d(CpGpApTpCpG)]2 and its fragments by high field NMR.

The two deoxyribonucleotides [d(CpGpApTpCpG)]2 and [d(CpGpCpG)]2 were synthesized by the phosphotriester method. Their duplex form under the conditions of the 1H-nmr experiments was proven by end 32P labeling with T4 polynucleotide kinase followed by butt end joining employing the absolute specifici...

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Bibliographische Detailangaben
Hauptverfasser: Lown, J W, Hanstock, C C, Bleackley, R C, Imbach, J L, Rayner, B, Vasseur, J J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC318681/
https://ncbi.nlm.nih.gov/pubmed/6709499
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