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Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG).

The structure of the crystalline daunomycin-d(CpGpTpApCpG) complex has been solved by x-ray diffraction analysis. The DNA forms a six-base-pair right-handed double helix with two daunomycin molecules intercalated in the d(CpG) sequences. The daunomycin aglycone chromophore is oriented at right angle...

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Detaylı Bibliyografya
Asıl Yazarlar: Quigley, G J, Wang, A H, Ughetto, G, van der Marel, G, van Boom, J H, Rich, A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1980
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC350470/
https://ncbi.nlm.nih.gov/pubmed/6938965
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