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alpha-DNA. I. Synthesis, characterization by high field 1H-NMR, and base-pairing properties of the unnatural hexadeoxyribonucleotide alpha-[d(CpCpTpTpCpC)] with its complement beta-[d(GpGpApApGpG)].

The novel deoxyribonucleotide alpha-[d(CpCpTpTpCpC)] and its complement beta-[d(GpGpApApGpG)] were synthesized by the phosphotriester method. 1H-NMR-NOE examination of the alpha-hexamer revealed that the cytosine and thymine bases appear to adopt anti conformations in this strand. In addition the de...

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Detalles Bibliográficos
Main Authors: Morvan, F, Rayner, B, Imbach, J L, Chang, D K, Lown, J W
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311508/
https://ncbi.nlm.nih.gov/pubmed/3725590
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