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alpha-DNA. I. Synthesis, characterization by high field 1H-NMR, and base-pairing properties of the unnatural hexadeoxyribonucleotide alpha-[d(CpCpTpTpCpC)] with its complement beta-[d(GpGpApApGpG)].

The novel deoxyribonucleotide alpha-[d(CpCpTpTpCpC)] and its complement beta-[d(GpGpApApGpG)] were synthesized by the phosphotriester method. 1H-NMR-NOE examination of the alpha-hexamer revealed that the cytosine and thymine bases appear to adopt anti conformations in this strand. In addition the de...

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Publicat a:Nucleic Acids Res
Autors principals: Morvan, F, Rayner, B, Imbach, J L, Chang, D K, Lown, J W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1986
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3725590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.12.5019
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