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Exploring the Topology of the Gid Complex, the E3 Ubiquitin Ligase Involved in Catabolite-induced Degradation of Gluconeogenic Enzymes

In the yeast Saccharomyces cerevisiae, key regulatory enzymes of gluconeogenesis such as fructose-1,6-bisphosphatase are degraded via the ubiquitin proteasome system when cells are replenished with glucose. Polyubiquitination is carried out by the Gid complex, a multisubunit ubiquitin ligase that co...

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Hlavní autoři: Menssen, Ruth, Schweiggert, Jörg, Schreiner, Jens, Kušević, Denis, Reuther, Julia, Braun, Bernhard, Wolf, Dieter H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408164/
https://ncbi.nlm.nih.gov/pubmed/22645139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363762
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