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iRhoms: ERADicating the messenger in growth control signaling
iRhoms are inactive rhomboid-like pseudoproteases that lack essential catalytic residues. Although iRhoms are highly conserved in metazoan species, little is known about their function. In a recent issue of Cell, Zettl et al. (2011) show that iRhoms regulate growth factor signaling through endoplasm...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408039/ https://ncbi.nlm.nih.gov/pubmed/21497754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.04.003 |
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