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iRHOM2 takes control of rheumatoid arthritis
The cytokine TNF-α is a major drug target for rheumatoid arthritis, an inflammatory joint disorder. An alternative approach is to target the protease TNF-α convertase (TACE), which releases TNF-α from cells. However, because TACE cleaves other proteins involved in development and cancer, a tissue-sp...
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| 1. autor: | |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561834/ https://ncbi.nlm.nih.gov/pubmed/23348732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67548 |
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