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Deoxyguanosine Forms a Bis-adduct with E,E-Muconaldehyde, an Oxidative Metabolite of Benzene. Implications for the Carcinogenicity of Benzene

Benzene is employed in large quantities in the chemical industry and is a ubiquitous contaminant in the environment. There is strong epidemiological evidence that benzene exposure induces hematopoietic malignancies, especially acute myeloid leukemia, in humans but the chemical mechanisms remain obsc...

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Hlavní autoři: Harris, Constance M., Stec, Donald F., Christov, Plamen P., Kozekov, Ivan D., Rizzo, Carmelo J., Harris, Thomas M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408037/
https://ncbi.nlm.nih.gov/pubmed/21972945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2002838
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