Attenuated response to methamphetamine sensitization and deficits in motor learning and memory after selective deletion of β-catenin in dopamine neurons

In the present study, we analyzed mice with a targeted deletion of β-catenin in DA neurons (DA-βcat KO mice) to address the functional significance of this molecule in the shaping of synaptic responses associated with motor learning and following exposure to drugs of abuse. Relative to controls, DA-...

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Bibliographische Detailangaben
Hauptverfasser: Diaz-Ruiz, Oscar, Zhang, YaJun, Shan, Lufei, Malik, Nasir, Hoffman, Alexander F., Ladenheim, Bruce, Cadet, Jean Lud, Lupica, Carl R., Tagliaferro, Adriana, Brusco, Alicia, Bäckman, Cristina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407939/
https://ncbi.nlm.nih.gov/pubmed/22822182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.026716.112
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