Attenuated response to methamphetamine sensitization and deficits in motor learning and memory after selective deletion of β-catenin in dopamine neurons

In the present study, we analyzed mice with a targeted deletion of β-catenin in DA neurons (DA-βcat KO mice) to address the functional significance of this molecule in the shaping of synaptic responses associated with motor learning and following exposure to drugs of abuse. Relative to controls, DA-...

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Detalhes bibliográficos
Main Authors: Diaz-Ruiz, Oscar, Zhang, YaJun, Shan, Lufei, Malik, Nasir, Hoffman, Alexander F., Ladenheim, Bruce, Cadet, Jean Lud, Lupica, Carl R., Tagliaferro, Adriana, Brusco, Alicia, Bäckman, Cristina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407939/
https://ncbi.nlm.nih.gov/pubmed/22822182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.026716.112
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