CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens

Methamphetamine (METH) produces increases in the expression of immediate early genes (IEGs) and of histone deacetylase 2 (HDAC2) in the rat nucleus accumbens (NAc). Here, we tested whether HDAC2 deletion influenced the effects of METH on IEG expression in the NAc. Microarray analyses showed no basel...

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Publicat a:Sci Rep
Autors principals: Torres, Oscar V., McCoy, Michael T., Ladenheim, Bruce, Jayanthi, Subramaniam, Brannock, Christie, Tulloch, Ingrid, Krasnova, Irina N., Cadet, Jean Lud
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547138/
https://ncbi.nlm.nih.gov/pubmed/26300473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13396
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