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Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats

Addiction is associated with neuroadaptive changes in the brain. In the present paper, we used a model of methamphetamine self-administration during which we used footshocks to divide rats into animals that continue to press a lever to get methamphetamine (shock-resistant) and those that significant...

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發表在:Sci Rep
Main Authors: Cadet, Jean Lud, Krasnova, Irina N., Walther, Donna, Brannock, Christie, Ladenheim, Bruce, McCoy, Michael T., Collector, Daniel, Torres, Oscar V., Terry, Ndeah, Jayanthi, Subramaniam
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108042/
https://ncbi.nlm.nih.gov/pubmed/27841313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37002
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