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Spatial and Temporal Requirements for huntingtin (Htt) in Neuronal Migration and Survival during Brain Development
Huntington's disease (HD), caused by an expanded triplet repeat in the huntingtin (Htt) gene, results in extensive neuropathology, but study of the Htt gene in CNS development through gene knockout is problematic as the knockout leads to embryonic lethality in mice. Here, we report that the kno...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407803/ https://ncbi.nlm.nih.gov/pubmed/21994396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2774-11.2011 |
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