Propylthiouracil Increases Sodium/Iodide Symporter Gene Expression and Iodide Uptake in Rat Thyroid Cells in the Absence of TSH

BACKGROUND: Propylthiouracil (PTU) and methimazole (MMI) are drugs that are widely used to treat Graves' disease. Although both exert an antithyroid effect primarily by blocking thyroid peroxidase activity, their molecular structure and other actions are different. We hypothesized that PTU and...

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מידע ביבליוגרפי
Main Authors: Sue, Mariko, Akama, Takeshi, Kawashima, Akira, Nakamura, Hannah, Hara, Takeshi, Tanigawa, Kazunari, Wu, Huhehasi, Yoshihara, Aya, Ishido, Yuko, Hiroi, Naoki, Yoshino, Gen, Kohn, Leonard D., Ishii, Norihisa, Suzuki, Koichi
פורמט: Artigo
שפה:Inglês
יצא לאור: Mary Ann Liebert, Inc. 2012
נושאים:
Thyroid Economy
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407387/
https://ncbi.nlm.nih.gov/pubmed/22853729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2011.0290
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