Propylthiouracil Increases Sodium/Iodide Symporter Gene Expression and Iodide Uptake in Rat Thyroid Cells in the Absence of TSH

BACKGROUND: Propylthiouracil (PTU) and methimazole (MMI) are drugs that are widely used to treat Graves' disease. Although both exert an antithyroid effect primarily by blocking thyroid peroxidase activity, their molecular structure and other actions are different. We hypothesized that PTU and...

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Dades bibliogràfiques
Autors principals: Sue, Mariko, Akama, Takeshi, Kawashima, Akira, Nakamura, Hannah, Hara, Takeshi, Tanigawa, Kazunari, Wu, Huhehasi, Yoshihara, Aya, Ishido, Yuko, Hiroi, Naoki, Yoshino, Gen, Kohn, Leonard D., Ishii, Norihisa, Suzuki, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Thyroid Economy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407387/
https://ncbi.nlm.nih.gov/pubmed/22853729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2011.0290
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