Propylthiouracil Increases Sodium/Iodide Symporter Gene Expression and Iodide Uptake in Rat Thyroid Cells in the Absence of TSH

BACKGROUND: Propylthiouracil (PTU) and methimazole (MMI) are drugs that are widely used to treat Graves' disease. Although both exert an antithyroid effect primarily by blocking thyroid peroxidase activity, their molecular structure and other actions are different. We hypothesized that PTU and...

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Bibliographische Detailangaben
Hauptverfasser: Sue, Mariko, Akama, Takeshi, Kawashima, Akira, Nakamura, Hannah, Hara, Takeshi, Tanigawa, Kazunari, Wu, Huhehasi, Yoshihara, Aya, Ishido, Yuko, Hiroi, Naoki, Yoshino, Gen, Kohn, Leonard D., Ishii, Norihisa, Suzuki, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Thyroid Economy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407387/
https://ncbi.nlm.nih.gov/pubmed/22853729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2011.0290
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