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Detection of Mycobacterium leprae DNA from Archaeological Skeletal Remains in Japan Using Whole Genome Amplification and Polymerase Chain Reaction

BACKGROUND: Identification of pathogen DNA from archaeological human remains is a powerful tool in demonstrating that the infectious disease existed in the past. However, it is very difficult to detect trace amounts of DNA remnants attached to the human skeleton, especially from those buried in a hu...

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Detalhes bibliográficos
Main Authors: Suzuki, Koichi, Takigawa, Wataru, Tanigawa, Kazunari, Nakamura, Kazuaki, Ishido, Yuko, Kawashima, Akira, Wu, Huhehasi, Akama, Takeshi, Sue, Mariko, Yoshihara, Aya, Mori, Shuichi, Ishii, Norihisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928730/
https://ncbi.nlm.nih.gov/pubmed/20865042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012422
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