Regulation of Dual Oxidase Expression and H(2)O(2) Production by Thyroglobulin

BACKGROUND: Thyroglobulin (Tg) is a macromolecular precursor in thyroid hormone synthesis to which iodine is stably bound. Tg, which is stored in the follicular space, is also a potent negative feedback regulator of follicular function, and this is achieved by suppressing mRNA levels of thyroid-spec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoshihara, Aya, Hara, Takeshi, Kawashima, Akira, Akama, Takeshi, Tanigawa, Kazunari, Wu, Huhehasi, Sue, Mariko, Ishido, Yuko, Hiroi, Naoki, Ishii, Norihisa, Yoshino, Gen, Suzuki, Koichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462396/
https://ncbi.nlm.nih.gov/pubmed/22874065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2012.0003
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