HILI Inhibits TGF-β Signaling by Interacting with Hsp90 and Promoting TβR Degradation

PIWIL2, called HILI in humans, is a member of the PIWI subfamily. This subfamily has highly conserved PAZ and Piwi domains and is implicated in several critical functions, including embryonic development, stem-cell self-renewal, RNA silencing, and translational control. However, the underlying molec...

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Autors principals: Zhang, Kun, Lu, Yilu, Yang, Ping, Li, Chao, Sun, Huaqin, Tao, Dachang, Liu, Yunqiang, Zhang, Sizhong, Ma, Yongxin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407066/
https://ncbi.nlm.nih.gov/pubmed/22848678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041973
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