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Piwil2 Inhibits Keratin 8 Degradation through Promoting p38-Induced Phosphorylation To Resist Fas-Mediated Apoptosis

The piwi-like 2 (piwil2) gene is widely expressed in tumors and protects cells from apoptosis induced by a variety of stress stimuli. However, the role of Piwil2 in Fas-mediated apoptosis remains unknown. Here, we present evidence that Piwil2 inhibits Fas-mediated apoptosis. By a bacterial two-hybri...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Jiang, Siyuan, Zhao, Lianfang, Lu, Yilu, Wang, Meiling, Chen, Yuan, Tao, Dachang, Liu, Yunqiang, Sun, Huaqin, Zhang, Sizhong, Ma, Yongxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386451/
https://ncbi.nlm.nih.gov/pubmed/25113562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00745-14
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