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Critical regulation of TGFβ signaling by Hsp90

Transforming growth factor β (TGFβ) controls a diverse set of cellular processes by activating TGFβ type I (TβRI) and type II (TβRII) serine-threonine receptor kinases. Canonical TGFβ signaling is mediated by Smad2 and Smad3, which are phosphorylated in their SXS motif by activated TβRI. The 90-kDa...

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Detalhes bibliográficos
Main Authors: Wrighton, Katharine H., Lin, Xia, Feng, Xin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453700/
https://ncbi.nlm.nih.gov/pubmed/18591668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800163105
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