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Critical regulation of TGFβ signaling by Hsp90
Transforming growth factor β (TGFβ) controls a diverse set of cellular processes by activating TGFβ type I (TβRI) and type II (TβRII) serine-threonine receptor kinases. Canonical TGFβ signaling is mediated by Smad2 and Smad3, which are phosphorylated in their SXS motif by activated TβRI. The 90-kDa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453700/ https://ncbi.nlm.nih.gov/pubmed/18591668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800163105 |
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