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Elevated IKKα Accelerates the Differentiation of Human Neuronal Progenitor Cells and Induces MeCP2-Dependent BDNF Expression

The IκB kinase α (IKKα) is implicated in the differentiation of epithelial and immune cells. We examined whether IKKα also plays a role in the differentiation and maturation of embryonic human neuronal progenitor cells (NPCs). We find that expression of an extra copy of IKKα (IKKα+) blocks self-rene...

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Bibliografske podrobnosti
Main Authors: Khoshnan, Ali, Patterson, Paul H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407048/
https://ncbi.nlm.nih.gov/pubmed/22848609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041794
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