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Subunit Interactions and Cooperativity in the Microtubule-severing AAA ATPase Spastin
Spastin is a hexameric ring AAA ATPase that severs microtubules. To see whether the ring complex funnels the energy of multiple ATP hydrolysis events to the site of mechanical action, we investigate here the cooperativity of spastin. Several lines of evidence indicate that interactions among two sub...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406712/ https://ncbi.nlm.nih.gov/pubmed/22637577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.291898 |
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