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Spastin's Microtubule-Binding Properties and Comparison to Katanin

Spastin and katanin are ring-shaped hexameric AAA ATPases that sever microtubules, and thus crucially depend on a physical interaction with microtubules. For the first time, we report here the microtubule binding properties of spastin at the single-molecule level, and compare them to katanin. Micros...

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Detalhes bibliográficos
Main Authors: Eckert, Thomas, Le, Doan Tuong-Van, Link, Susanne, Friedmann, Lena, Woehlke, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521757/
https://ncbi.nlm.nih.gov/pubmed/23272056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050161
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