Phosphorylation of Mycobacterial PcaA Inhibits Mycolic Acid Cyclopropanation: CONSEQUENCES FOR INTRACELLULAR SURVIVAL AND FOR PHAGOSOME MATURATION BLOCK

Pathogenic mycobacteria survive within macrophages by residing in phagosomes, which they prevent from maturing and fusing with lysosomes. Although several bacterial components were seen to modulate phagosome processing, the molecular regulatory mechanisms taking part in this process remain elusive....

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Detalhes bibliográficos
Main Authors: Corrales, Rosa Milagros, Molle, Virginie, Leiba, Jade, Mourey, Lionel, de Chastellier, Chantal, Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406704/
https://ncbi.nlm.nih.gov/pubmed/22621931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373209
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